HKB
Before we can have any tolerable knowledge of this kind, we must First know what changes the primary qualities of one body do regularly produce in the primary qualities of another, and how. Secondly, We must know what primary qualities of any body produce certain sensations or ideas in us. This is in truth no less than to know ALL the effects of matter, under its divers modifications of bulk, figure, cohesion of parts, motion and rest. Which, I think every body will allow, is utterly impossible to be known by us without revelation. Nor if it were revealed to us what sort of figure, bulk, and motion of corpuscles would produce in us the sensation of a yellow colour, and what sort of figure, bulk, and texture of parts in the superficies of any body were fit to give such corpuscles their due motion to produce that colour; would that be enough to make universal propositions with certainty, concerning the several sorts of them; unless we had faculties acute enough to perceive the precise bulk, figure, texture, and motion of bodies, in those minute parts, by which they operate on our senses, so that we might by those frame our abstract ideas of them. I have mentioned here only corporeal substances, whose operations seem to lie more level to our understandings. For as to the operations of spirits, both their thinking and moving of bodies, we at first sight find ourselves at a loss; though perhaps, when we have applied our thoughts a little nearer to the consideration of bodies and their operations, and examined how far our notions, even in these, reach with any clearness beyond sensible matter of fact, we shall be bound to confess that, even in these too, our discoveries amount to very little beyond perfect ignorance and incapacity.